Results 281 to 290 of about 4,919,732 (395)

Ultrasound‐Mediated Biotransfection of Engineered Bone Marrow Mesenchymal Stem Cells in Treated Bone Defects through Intracellular Cavitation

open access: yesAdvanced Science, EarlyView.
Ultrasound‐mediated biotransfection through intracellular cavitation increases plasmid nuclear translocation and gene transfection efficiency by 284.7% and 131.6% in engineered bone marrow mesenchymal stem cells (BMSCs) compared to traditional ultrasound‐targeted microbubble destruction techniques. The maintained bone morphogenetic protein 2 expression
Zhili Xu   +7 more
wiley   +1 more source

Cut‐Enabled Mechanical Metamaterials for Multimodal and Reprogrammable Static Nonreciprocity

open access: yesAdvanced Science, EarlyView.
Cut‐enabled mechanical metamaterials are designed to overcome the challenge of obtaining multiple and reprogrammable static nonreciprocal modes in a single microstructural topology. It offers a pathway to synthesize multiple nonreciprocal modes and control the nonreciprocal responses, enhancing the functionality of metamaterials.
Jinhao Zhang   +8 more
wiley   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

open access: yesAdvanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang   +12 more
wiley   +1 more source

High-frequency and high-amplitude sounds enhance bird deterrence. [PDF]

open access: yesSci Rep
Dong ZJ   +5 more
europepmc   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

open access: yesAdvanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao   +16 more
wiley   +1 more source

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