Results 151 to 160 of about 192,617 (260)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Editorial: Improving the reporting and sound methodology of scientific articles: introduction of an editorial series. [PDF]

Acta Orthop
Overgaard S, Christensen R, Rogmark C, Rasmussen JV, Hvid I, Westberg M, Helenius I, Mäkelä K, Gosens T, Randsborg PH, Pijls BG, Gerdhem P, Wagner P, Felländer-Tsai L, Reito A.   +14 more
europepmc   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Ultrafast Optoacoustics Reveals Intricate 3D Anisotropic Elasticity in Nanocrystalline Membranes

Advanced Science, EarlyView.
Ultrafast optoacoustic spectroscopy combined with a Sagnac interferometer enables non‐contact, simultaneous characterization of thickness and the full three‐dimensional anisotropic elastic constants in freestanding nanocrystalline copper membranes. By capturing gigahertz Lamb waves and zero‐group‐velocity resonances followed by SAFE‐GA inversion, the ...
Shuchang Zhang, Yi He, Guojie Luo, Jie Huang, Pak San Yip, Haoyu Cui, Wanglinhan Zhang, Zijian Wang, Lin Ye, Yang Lu, Zhongqing Su, Yehai Li   +11 more
wiley   +1 more source

Enhancing SELD Performance: The Role of Data Augmentation Techniques in Spatial Sound Analysis. [PDF]

Sensors (Basel)
Santamaria C, Grijalva F, Rosero K, Vega-Sánchez J, Garzón NO, Mora HC.   +5 more
europepmc   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

A Synchronous Triggering Method for Impact Artificial Seismic Source and Seismographs Based on Non-Contact Audio Detection. [PDF]

Sensors (Basel)
Wang W, Yang Y, Wang S, Wang Z, Hu J, Shi Y, Fu Z.   +6 more
europepmc   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source

A general mechanism of airborne hearing in recent and early non-tympanate tetrapods. [PDF]

J Exp Biol
Christensen-Dalsgaard J, Lauridsen TB, Capshaw G, Carr CE.   +3 more
europepmc   +1 more source

Relaxor Ferroelectricity Enables Enhanced Thermoelectric Performance in In2Se3‐Alloyed GeTe

Advanced Science, EarlyView.
A non‐equimolar In3+/Se2− alloying strategy creates Ge vacancies in GeTe, inducing relaxor ferroelectricity that broadens the low thermal conductivity window. Simultaneously, cubic phase stabilization broadens optimal electrical transport, achieving an average zT > 1.0 over 330–625 K.
Yuting Zhang, Yang Li, Jianguo Chen, Kai Guo, Jun Luo, Jiye Zhang   +5 more
wiley   +1 more source