A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Volatilome, Microbial, and Sensory Profiles of Coffee Leaf and Coffee Leaf-Toasted Maté Kombuchas. [PDF]
Sales AL +7 more
europepmc +1 more source
Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites
Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer +6 more
wiley +1 more source
Unusual Swelling Behavior of Hydrogels Modified with Spiropyran as Appendage or Crosslinker
Not so innocent after all—spiropyran crosslinkers in methylenebisacrylamide‐crosslinked poly(acrylamide‐co‐acrylic acid) hydrogels increase crosslinking density, but also, counterintuitively, increase swelling. Charge complexation, cooperative chemo‐mechanical effects, and aggregation may explain these observations.
Michael M. Lerch +7 more
wiley +1 more source
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
<i>Parageobacillus</i> and <i>Geobacillus</i> spp.: From Food Spoilage to Beneficial Food Applications. [PDF]
Salvador M, Condón S, Gayán E.
europepmc +1 more source
This work presents a continuous linear gradient catalyst layer design, a general strategy for improving membrane electrode assemblies across electrochemical devices. Fabricated via a dual‐nozzle spray coating method, the architecture controls the Pt/carbon ratio, ionomer content and ionomer type across the catalyst layer, enhancing proton conduction ...
Shangwei Zhou +15 more
wiley +1 more source
Crude Blueberry Phenolic Extracts Improve Gut Barrier Integrity and Exert Anti-Inflammatory and Antimicrobial Activity in an In Vitro Weaning Stress Model. [PDF]
Nathan VB, Eckrote S, Li S, Reddivari L.
europepmc +1 more source
Three‐dimensional Antimony Sulfide Based Flat Optics
This work presents the development of a grayscale electron beam lithography (g‐EBL) method for fabricating antimony trisulfide (Sb2S3) nanostructures with customizable 3D profiles. The refractive index of g‐EBL patterned Sb2S3 is determined based on the synergy of genetic algorithm and transfer matrix method.
Wei Wang +18 more
wiley +1 more source
Revealing the dynamic changes in the metabolites and sensory quality of Citri Reticulatae Pericarpium during aging using feature-based molecular networks and metabolomics. [PDF]
Xu K +6 more
europepmc +1 more source

