Results 241 to 250 of about 17,122,186 (353)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Supplementary material to "Quantification of Methane Sources in the Athabasca Oil Sands Region of Alberta by Aircraft Mass-Balance"

, 2017
Sabour Baray, Andrea Darlington, Mark Gordon, Katherine Hayden, Amy Leithead, Shao‐Meng Li, Peter S. K. Liu, R. L. Mittermeier, Samar G. Moussa, Jason M. O’Brien, Ralf M. Staebler, Mengistu Wolde, Doug Worthy, R. McLaren   +13 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Sources of Oral Health Activities Among Croatian University Students-A Pilot Study. [PDF]

Dent J (Basel)
Aranza D, Poklepović Peričić T, Milavić B.   +2 more
europepmc   +1 more source

New fungal sources for α-L-Rhamnosidase: an important enzyme used in the synthesis of drugs and drug precursors

, 2008
Vinita Yadav, Vinita Yadav, K. D. S. Yadav   +2 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Reply to Nishimura, "Questions regarding mortality and infection source in deep-seated infections". [PDF]

Antimicrob Agents Chemother
Slain N, Kunz Coyne AJ.
europepmc   +1 more source

Distance Measurement-Based Cooperative Source Localization: A Convex Range-Free Approach

, 2013
Fatma Kiraz
openalex   +1 more source