Results 151 to 160 of about 1,277,548 (269)

Comparison of a Free-Field and a Closed-Field Sound Source Identification Paradigms in Assessing Spatial Acuity in Adults With Normal Hearing Sensitivity. [PDF]

J Audiol Otol, 2023
Sampath S, Aisha S, Neelamegarajan D, Jain C, Nisha KV.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

From source identification to preferential interventions: Determinants of a workplace mental health promotion program to control workplace stress among health care workers based on a qualitative study. [PDF]

PLoS One
Zeinolabedini M, Motlagh ME, Heidarnia A, Shakerinejad G.   +3 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Acanthamoeba Infection in a Hematopoietic Cell Transplant Recipient: Challenges in Diagnosis, Management, and Source Identification. [PDF]

Transpl Infect Dis
Banerjee CT, Conlan S, Mostaghim A, Michelin A, Arduino M, Mattioli M, Haston JC, Das S, Seyedmousavi A, Chang BH, O'Connell EM, Kanakry CG, Dilara A, Quezado M, Gea-Banacloche J, Deming C, Segre JA, Han A, Cuellar-Rodriguez J.   +18 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Chemical characterization and source identification of PM_2.5 in the Huaxi urban area of Guiyang. [PDF]

Sci Rep
Li Y, Wang X, Xu P, Gui J, Guo X, Yan G, Fei X, Yang A.   +7 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Assessment and management of arsenic contamination in groundwater from Sanso, Ghana: Health risk implications, source identification, adsorption and immobilization for safe disposal. [PDF]

Toxicol Rep
Ankapong M, Ashong GW, Adjaottor AA, Ababio BA, Kwaansa-Ansah EE, Toku M.   +5 more
europepmc   +1 more source