Results 71 to 80 of about 4,442,388 (297)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2020 Studies to develop understandings of rolling noise, which has great influence on wayside noise in the frequency range 250 Hz to 4k Hz, have been carried out widely by measurements and theoretical models.
Tsugutoshi KAWAGUCHI +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Utilization of beamforming in sound source localization applications
, 2015 This paper deals with utilization of beamforming in acoustic source localization using static microphone array with fixed geometry. It describes main principle of delay and sum beamformer and its practical implementation in localization system ...
Dostálek, Petr +2 more
core +1 more source
rodrigo-pena/src-localization-graphs: src-localization-graphs-v0.1-alpha-dev
, 2016 Matlab implementation of an algorithm for source localization on graphs via l1 regularization and spectral graph theory. Working examples.
Rodrigo Pena (6272066)
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Sound Source Localization and Separation [PDF]
, 2006 People face the problem of sound source localization and separation in situations where they attempt to localize and focus on a source of sound among a dissonance of conversations and background noise.
Taddese, Biniyam Tesfaye
core +2 more sources
Study Of Acoustic Source Localization Algorithm For Planar Arrays
, 2010 The source localization algorithms in the earlier works, mostly used non-planar arrays. If we consider scenarios like human-computer communication, or human-television communication where the microphones need to be placed on the computer monitor or ...
Hari, KVS, Naganjaneyulu, GVSSKR
core