Results 81 to 90 of about 1,016,942 (262)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Identification of source location in a single-sided building with natural ventilation: Case of interunit pollutant dispersion. [PDF]

J Build Eng, 2023
Dai Y, Zhang F, Wang H.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Age-related differences in eating location, food source location, and timing of snack intake among U.S. children 1-19 years. [PDF]

Int J Behav Nutr Phys Act, 2023
Tripicchio GL, Croce CM, Coffman DL, Pettinato C, Fisher JO.   +4 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Retracted: Research on Microseismic Source Location Method Based on Waveform Characteristics Monitored by Nanomaterial Sensor under the Background of Metal Oxide Polluted Environment. [PDF]

Bioinorg Chem Appl, 2023
And Applications BC.
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Rapid estimation of viral emission source location via genetic algorithm. [PDF]

Comput Mech, 2022
Clemon LM.
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Deep Learning‐Based 3D Microseismic Event Direct Location Using Simultaneous Surface and Borehole Data

Journal of Geophysical Research: Machine Learning and Computation
Microseismic monitoring is crucial for characterizing and assessing fracture systems developed during subsurface operations like geothermal reservoir development, CO2 sequestration, and hydraulic fracturing.
Yuanyuan Yang, Omar M. Saad, Tariq Alkhalifah   +2 more
doaj   +1 more source