Results 51 to 60 of about 2,393,541 (218)
Revista Ingenierías Universidad de MedellínThis article presents the development of a model for deploying software processes within the context of free and open-source software FLOSS communities, characterized by the voluntary participation of people geographically distributed in different ...
FABIAN ALONSO LARA VARGAS +1 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
OPEN-SOURCE MOODLE SOFTWARE ADAPTATION SUPPORTING MEDICAL UNIVERSITY ACADEMIC PROCESS
Medična Informatika ta Inženerìâ, 2014 An open-source software application is an important part of the modern approach to the medical education. The experience of the Moodle learning management system in Ternopil State Medical University by I. Ya.
A. V. Semenets
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Deep Gaussian Process-Based Bayesian Inference for Contaminant Source Localization
IEEE Access, 2018 This paper proposes a Bayesian framework for localization of multiple sources in the event of accidental hazardous contaminant release. The framework assimilates sensor measurements of the contaminant concentration with the integrated multizone ...
Young-Jin Park +2 more
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Design of a Gas Permeation and Pervaporation Membrane Model for an Open Source Process Simulation Tool. [PDF]
Membranes (Basel), 2022 Aziaba K +3 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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ОСОБЕННОСТИ ЭЛЕКТРОМАГНИТНЫХ ПРОЦЕССОВ В 4Q-S ПРЕОБРАЗОВАТЕЛЕ ПРИ ПИТАНИИ ОТ ОДНОФАЗНОГО ИСТОЧНИКА
Elektrotehnìka ta Elektroenergetika, 2008 Исследованы особенности электромагнитных процессов в 4q-s преобразователе при питании от однофазного источника. Выявлены особенности режимов работы фильтров, связанные с ограниченной частотой коммутации полностью управляемых силовых ключей.
N. I. Falaleev
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Geoscience Letters, 2019 Stress drops of small earthquakes have been estimated under the assumption that the rupture propagates symmetrically within a circular fault. However, recent studies have observed directivity effects on seismic waves even for small earthquakes.
Keisuke Yoshida
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