Results 131 to 140 of about 10,574,194 (321)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Denoising source separation

, 2004
A new algorithmic framework called denoising source separation (DSS) is introduced. The main benefit of this framework is that it allows for easy development of new source separation algorithms which are optimised for specific problems. In this framework, source separation algorithms are constucted around denoising procedures.
Särelä, Mr Jaakko, Valpola, Dr Harri
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Factors Influencing Source Separation Intention for Improving Waste Management in Educational Places: A Case Study for a University Campus

International Journal of Environmental Health Engineering
Aim: This research addresses gaps in waste management practices and promotes sustainable waste management initiatives at the university level. Methods: This study investigates the factors influencing source separation intention to improve waste ...
Edris Hoseinzadeh, Mahdi Farzadkia, Ghodratollah Roshanaei, Alireza Hosseinbaba   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Simultaneous inactivation of antibiotic-resistant bacteria and degradation of antibiotic-resistant genes in alkalised human urine

Frontiers in Microbiology
The coexistence of pharmaceuticals and microorganisms in source separated urine poses a risk for the development of antimicrobial resistance (AMR), especially when urine-based fertilizers are applied to soils.
Natnael Demissie, Natnael Demissie, Annika Nordin, Prithvi Simha, Isis Conroy, He Sun, Anna Schnürer, Björn Vinnerås, Adey Desta, Adey Desta   +9 more
doaj   +1 more source

Concatenate Convolutional Neural Networks for Non-Intrusive Load Monitoring across Complex Background

Energies, 2019
Non-Intrusive Load Monitoring (NILM) provides a way to acquire detailed energy consumption and appliance operation status through a single sensor, which has been proven to save energy.
Qian Wu, Fei Wang
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Speech Segregation based on Pitch Track Correction and Music-Speech Classification

Advances in Electrical and Computer Engineering, 2012
A novel approach for pitch track correction and music-speech classification is proposed in order to improve the performance of the speech segregation system.
KIM, H.-G., JANG, G.-J., PARK, J.-S., KIM, J.-H., OH, Y.-H.   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source