Results 191 to 200 of about 6,052,198 (305)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Mapping Quality Indicators in Primary Health Care: A Scoping Review of Contemporary Approaches and Persistent Measurement Gaps. [PDF]

Healthcare (Basel)
Triantafyllou C, Ntikoudi A, Papachristou A, Psiakis V, Fonseca VR, Breda J.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Human food sources shape routine movements across elevational gradients in an alpine bird. [PDF]

Mov Ecol
Beck KB, Loretto MC, Müller T.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Average monthly income from palm oil cultivation [PDF]

, 2010
Various government sources
core   +1 more source

Assessing the use of the input of care users in long-term care homes during 2020-2023 in the Netherlands: an exploratory study. [PDF]

BMJ Open Qual
Palimetaki F, Schouteten R.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Ghana’s Cinematic Past: An Interview with Dr Jim Fara Panbonor Awindor

Sources
Anita Afonu, Dan Hodgkinson, Jim Fara Panbonor Awindor   +2 more
doaj   +1 more source

Assessing methods to identify Veterans Health Administration populations with Veterans Justice Programs contact to improve health research. [PDF]

PLoS One
Finlay AK, Binswanger I, Harris AHS, Stimmel M, Yu M, Singh K, Tsai J.   +6 more
europepmc   +1 more source