Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
TikTok and YouTube as sources of information on anal fissure: A comparative analysis. [PDF]
Front Public Health, 2022 Chen Z, Pan S, Zuo S.
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Exploring the Relationship Between Conspiracy Theory Beliefs and Adherence to Government Guidelines During the COVID-19 Pandemic: The Role of Perceived Control and Trust in Social Media and Traditional Sources of Information. [PDF]
Healthcare (Basel)Epifanio MS +5 more
europepmc +1 more source
"Menstruation is a Fearful Thing": A Qualitative Exploration of Menstrual Experiences and Sources of Information About Menstruation Among Adolescent Schoolgirls. [PDF]
Int J Womens Health, 2023 Betsu BD +3 more
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
From Knowledge to Habits: Changes in COVID-19 Health Attitudes, Practices, and Sources of Information (HAPS) at Qatar University Post-Pandemic. [PDF]
Health Sci RepAlkaabi I +4 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
MVGNet: Prediction of PI3K Inhibitors Using Multitask Learning and Multiview Frameworks
ACS OmegaYanlei Kang +3 more
doaj +1 more source
Search engines and short video apps as sources of information on acute pancreatitis in China: quality assessment and content assessment. [PDF]
Front Public HealthJiang S, Zhou Y, Qiu J, Gou X.
europepmc +1 more source