Results 81 to 90 of about 7,261,541 (287)
Process Performance Analysis in Large-Scale Systems Integrating Different Sources of Information
, 2012 Process auditing using historical data can identify causes for poor performance and reveal opportunities to improve process operation. To date, the data used has been limited to process measurements; however other sources hold complementary information ...
Bauer +19 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
INFORMATION BASE OF ENSURING ECONOMIC SECURITY OF THE ENTERPRISE
Вестник Российского экономического университета имени Г. В. Плеханова, 2017 The article deals with specific features of the information base functioning, which is used to ensure economic security of the enterprise. The author pays attention to principle official sources, gives their brief characteristics and shows opportunities ...
Eugene O. Savchenko
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Pump-Probe Detection of Diamond Ionization and Ablation Induced by Ultra-Fast Laser
PhotonicsDiamond, widely used in optoelectronic devices, plays a crucial role in improving performance through studies of its electronic structure and optoelectronic response. This study combines computational methods and experiments for analysis.
Jinpeng Duan +5 more
doaj +1 more source
Active Ontology: An Information Integration Approach for Dynamic Information Sources [PDF]
, 2007 In this paper we describe an ontology-based information integration approach that is suitable for highly dynamic distributed information sources, such as those available in Grid systems.
Corcho, Oscar +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Multi-Source Neural Variational Inference
, 2018 Learning from multiple sources of information is an important problem in machine-learning research. The key challenges are learning representations and formulating inference methods that take into account the complementarity and redundancy of various ...
Günnemann, Stephan +2 more
core +1 more source