Results 81 to 90 of about 86,044 (217)

The Effect of Online Parent Training With and Without Coaching Support on the Well‐Being of Families of Children With Neurodisabilities: A Randomized Controlled Trial

open access: yesAutism Research, EarlyView.
ABSTRACT Families of children with neurodisabilities often face significant child behavioral challenges that can affect overall family functioning and well‐being. This randomized controlled trial (RCT) used family resilience theory as the investigative framework to examine the impact of an online parenting program designed to address child behavioral ...
Jeffrey McCrossin   +9 more
wiley   +1 more source

Variation for Nitrogen Use Efficiency Traits in Wheat Under Contrasting Nitrogen Treatments in South-Eastern Europe. [PDF]

open access: yesFront Plant Sci, 2021
Ivić M   +13 more
europepmc   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Association of polygenic risk scores, traumatic life events and coping strategies with war-related PTSD diagnosis and symptom severity in the South Eastern Europe (SEE)-PTSD cohort. [PDF]

open access: yesJ Neural Transm (Vienna), 2022
Weber H   +30 more
europepmc   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan   +24 more
wiley   +1 more source

The European Experience of Ensuring the Development of River Shipping Companies [PDF]

open access: yesProblemi Ekonomiki, 2015
The aim of the article is to study the features of the inland waterway transport development in the European countries to define the main ways of development of the shipping European Union countries and the use of their experience for inland navigation ...
Tymoshchuk Olena M.   +1 more
doaj  

Relationships among nitrous oxide exposure, neurological injury and biomarkers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel   +6 more
wiley   +1 more source

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