Characterization of Monoclonal Antibodies to Junin Virus Nucleocapsid Protein and Application to the Diagnosis of Hemorrhagic Fever Caused by South American Arenaviruses [PDF]
Clinical and Vaccine Immunology, 2009 ABSTRACT Junin virus (JUNV), Machupo virus, Guanarito virus, Sabia virus, and Chapare virus are members of New World arenavirus clade B and are the etiological agents of viral hemorrhagic fevers that occur in South America. In this study, we produced three monoclonal antibodies (MAbs) to the recombinant nucleocapsid protein of JUNV ...
Nakauchi, Mina +7 more
openaire +5 more sources
South American Arenaviral Hemorrhagic Fevers
, 2015 Viral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases.
Stephan, Betina Inés +3 more
openaire +2 more sources
Uirusu, 2022 South American Hemorrhagic Fever is caused by the Arenavirus, which belong to the Family Arenaviridae, genus mammarenavirus, infection at South America. South American Hemorrhagic Fever includes 1. Argentinian Hemorrhagic fever caused by Junin virus, 2. Brazilian hemorrhagic fever caused by Sabia virus, 3.
Meion, Lee +3 more
openaire +2 more sources
Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers
, 2010 C.J. PETERS
openaire +2 more sources
Site 1 Protease Is Required for Proteolytic Processing of the Glycoproteins of the South American Hemorrhagic Fever Viruses Junin, Machupo, and Guanarito [PDF]
Journal of Virology, 2008 ABSTRACT The cellular proprotein convertase s ite 1 p rotease (S1P) has been implicated in the proteolytic processing of the glycoproteins (GPs) of Old World arenaviruses. Here we report that S1P is also involved in the processing of the GPs of the genetically more-distant South ...
Rojek, Jillian M. +4 more
openaire +3 more sources
Rodent-borne emerging viral zoonosis. Hemorrhagic fevers and hantavirus infections in South America [PDF]
, 2000 Fil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.Fil: Pinheiro, F. Communicable Disease Program, Pan American Health Organization/World Health Organization, Washington, DC (FP); Estados Unidos ...
Enria, Delia, Pinheiro, F
core +1 more source
Interim Report on SNP analysis and forensic microarray probe design for South American hemorrhagic fever viruses, tick-borne encephalitis virus, henipaviruses, Old World Arenaviruses, filoviruses, Crimean-Congo hemorrhagic fever viruses, Rift Valley fever [PDF]
, 2012 The goal of this project is to develop forensic genotyping assays for select agent viruses, enhancing the current capabilities for the viral bioforensics and law enforcement community. We used a multipronged approach combining bioinformatics analysis, PCR-enriched samples, microarrays and TaqMan assays to develop high resolution and cost effective ...
Jaing, C, Gardner, S
openaire +2 more sources
Antibody-based inhibition of pathogenic new world hemorrhagic fever mammarenaviruses by steric occlusion of the human transferrin receptor 1 apical domain [PDF]
, 2021 Pathogenic clade B New World mammarenaviruses (NWM) can cause Argentine, Venezuelan, Brazilian, and Bolivian hemorrhagic fevers. Sequence variability among NWM glycoproteins (GP) poses a challenge to the development of broadly neutralizing therapeutics ...
Clark, Lars E. +15 more
core +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Putting Rodents at the Center of One Health Programs: A Narrative Synthesis
Integrative Zoology, EarlyView.Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley +1 more source