Results 171 to 180 of about 1,965,914 (265)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Factors Influencing Occupational Grief Among Pediatric Emergency and Intensive Care Unit Nurses in South China: A Cross-Sectional Study. [PDF]

J Nurs Manag
Liang Y, Jiang X, Peng Y, Sun L, Liu H, Chen J, Zhou Y, Luo Y, Shi X, Yin C.   +9 more
europepmc   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

InVEST Model and Landscape Indices Reveal Habitat Quality Degradation From Land Use Changes in South China. [PDF]

Ecol Evol
Wang X, Liu G, Jia H.
europepmc   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Prognostic model of HIV-associated talaromycosis in south China: A large-scale retrospective study. [PDF]

PLoS Negl Trop Dis
Lin W, He Y, Chen X, Zeng M, Zhang H, Guo P, Xu F, Liu B, Chen X, He H, Tang X, Li L.   +11 more
europepmc   +1 more source

Boosting Fast‐Charging Performance of Ni‐Rich NCM9055 Cathodes with Nb2O5 Dual Functional Modification

Advanced Science, EarlyView.
A dual‐functional Nb2O5 modulation strategy is reported to overcome kinetic limitations in Ni‐rich cathodes. The formation of LiNbO3 phase at the grain boundary of the polycrystalline NCM9055 cathode preserves a radially aligned microstructure and establishes fast lithium‐ion pathways.
Tian Rao, Zhaowen Bai, Jian Wang, Yang Ren, Qingsong Weng, Zhongzhu Liu, Maxim Avdeev, Robson Monteiro, Luanna Parreira, Xuejie Huang, Guohua Chen, Yongming Zhu   +11 more
wiley   +1 more source

Characterizing the Evolution of Inter-Actor Networks in the South China Sea Arbitration via Entropy-Driven Graph Representation Learning from Massive Media Event Data. [PDF]

Entropy (Basel)
Ma M, Yu H, Fang P.
europepmc   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source