Results 211 to 220 of about 2,074,788 (313)

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

open access: yesAdvanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu   +18 more
wiley   +1 more source

Electronic‐State Polarization Engineering‐Regulated Fluorinated Covalent Organic Framework Nanocables for Fast Lithium‐Ion Storage

open access: yesAdvanced Science, EarlyView.
Electronic‐state polarization engineering is realized by constructing fluorinated COF nanocables on conductive CNTs scaffolds. The polar C─F units generate localized electric fields and strong ion‐dipole interactions, promoting Li+ adsorption and transport.
Kaifu Xu   +5 more
wiley   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Electrostatic Potential Complementarity for Thickness‐Tolerant Cathode Interlayers in High‐Efficiency Organic and Tandem Solar Cells

open access: yesAdvanced Science, EarlyView.
Two model molecules — trimesic acid (TMA) and phloroglucinol (PG) — with opposite central electrostatic potential (ESP) distributions are employed to elucidate how molecular electrostatic interactions regulate the cathode interlayer (CIL) PDINN. Electrostatic potential complementarity is revealed as the intrinsic origin of thickness sensitivity in CILs,
Xiaoman Ding   +13 more
wiley   +1 more source

Rapid in situ range testing for acoustic telemetry in Leizhou Bay, South China Sea. [PDF]

open access: yesSci Rep
Lyu S   +7 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

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