Results 31 to 40 of about 6,550,099 (252)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

FY02-03 Accountability Report South Carolina Sea Grant Consortium [PDF]

open access: yes, 2003
The South Carolina Sea Grant Consortium reports to the Office of State Budget its annual accountability report that includes an organization chart, comparative summary of statistics, and report of programs of the Ethics ...
South Carolina Sea Grant Consortium
core   +1 more source

China floating nuclear power plants in South China Sea [PDF]

open access: yes, 2023
China has been toying with the idea of developing floating nuclear power plants for its islands in East Sea and South China Sea. This idea germinated after it was felt that in order to sustain better radar and signals interception facility in the islands
Jha, Pankaj
core  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

What are Australia’s national security interests in the South China Sea? [PDF]

open access: yes, 2015
This paper examines Australia’s national security interests in the South China Sea. It notes that a number of states lay claim to various islands in the region, and that territorial disputes over those claims have occasionally erupted into armed conflict
Richard Keir
core  

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang   +23 more
wiley   +1 more source

FY03-04 Accountability Report South Carolina Sea Grant Consortium [PDF]

open access: yes, 2004
The South Carolina Sea Grant Consortium reports to the Office of State Budget its annual accountability report that includes an organization chart, comparative summary of statistics, and report of programs of the Ethics ...
South Carolina Sea Grant Consortium
core   +1 more source

Establishing a national marine park in the South China Sea: legal framework necessity, feasibility assessment, and governance solutions for marine environmental protection

open access: yesFrontiers in Marine Science
Establishing a National Marine Park (NMP) in the South China Sea (SCS) plays a pivotal role in protecting marine biodiversity, mitigating ecological threats caused by human activities, and promoting sustainable development.
Yuwen Huang
doaj   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton   +4 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

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