Results 31 to 40 of about 78,828 (304)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

What are Australia’s national security interests in the South China Sea? [PDF]

open access: yes, 2015
This paper examines Australia’s national security interests in the South China Sea. It notes that a number of states lay claim to various islands in the region, and that territorial disputes over those claims have occasionally erupted into armed conflict
Richard Keir
core  

UNCLOS Navigational Regimes and their Significance for the South China Sea

open access: yes, 2021
Research on The United Nations Convention on the Law of the Sea (UNCLOS) is a valuable addition to understanding the political situation in the potentially volatile South China Sea region.
Rothwell, Donald
core  

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Establishing a national marine park in the South China Sea: legal framework necessity, feasibility assessment, and governance solutions for marine environmental protection

open access: yesFrontiers in Marine Science
Establishing a National Marine Park (NMP) in the South China Sea (SCS) plays a pivotal role in protecting marine biodiversity, mitigating ecological threats caused by human activities, and promoting sustainable development.
Yuwen Huang
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Interannual variations of bomb radiocarbon during 1977-1998 recorded in coral from Daya Bay, South China Sea

open access: yes, 2003
22 annual layered samples of coral from 1977 to 1998 were collected from Daya Bay, South China Sea, their bomb-C-14 (nuclear weapons testing C-14) concentrations were determined and studied, and the atmosphere-sea exchange rate and diffusion thickness ...
Zhou, B   +5 more
core   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

From Declarations to Negotiations: ASEAN’s Role in Managing the South China Sea Dispute [PDF]

open access: yesContemporary Chinese Political Economy and Strategic Relations: An International Journal
In 2023 and 2024, tensions in the South China Sea (SCS) escalated among some claimant states, especially between the People’s Republic of China and the Philippines over the Shoals of Scarborough, Second Thomas, and Sabina.
Vo Xuan Vinh   +2 more
doaj  

JNK1 derived from orange-spotted grouper, Epinephelus coioides, involving in the evasion and infection of Singapore grouper iridovirus (SGIV)

open access: yesFrontiers in Microbiology, 2016
c-Jun N-terminal kinase (JNK) regulates cellular responses to various extracellular stimuli, environmental stresses, pathogen infections, and apoptotic agents. Here, a JNK1, Ec-JNK1, was identified from orange-spotted grouper, Epinephelus coioides.
Minglan eGuo   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy