Results 41 to 50 of about 284,346 (260)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Regional Educational Performance Patterns in Europe

open access: yesCenter for Educational Policy Studies Journal, 2011
The paper aims to contribute to the assessment of the contextual relevance of various educational policies through an analysis of three aspects of the performance profiles of European countries: participation, the quality of learning outcomes and the ...
Péter Radó
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Dinamica demografică în perioada post-1945 și implicațiile ei (geo)politice (Demographic Trends Since 1945 and its (Geo)Politics Influences) [PDF]

open access: yesPolis: Revista de Stiinte Politice, 2016
The world population has constantly increased post-1945. This trend has been unequal, there were significant differences between both continental & regional, developed & underdeveloped spaces. The increase in the developing world has been contra-balanced
Aurelian GIUGĂL
doaj  

Creative Pluralism in Indian and Romanian Accounts of Transnational Migration

open access: yesAmerican, British and Canadian Studies Journal, 2016
The paper offers a comparative perspective on transmigrant cultural identities as illustrated in the works of two contemporary South Asian American and Romanian American authors, Jhumpa Lahiri and Aura Imbăruș.
Stoican Adriana Elena
doaj   +1 more source

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background Immune checkpoint inhibitors (ICI) have radically changed cancer therapy, but most patients with cancer are unresponsive or relapse after treatment. MK-5890 is a CD27 agonist antibody intended to complement ICI therapy. CD27 is a member of the
David Rosen   +35 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

11th Congress of South-East European Studies. Sofia 2015

open access: yesColloquia Humanistica, 2015
11th Congress of South-East European Studies. Sofia 2015 The 11th Congress of South-East European Studies took place in Sofia, Bulgaria, between 31 August and 4 September 2015.
Mirella Korzeniewska-Wiszniewska
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Operational Framework for Large-Scale Power-to-X Plants Fed by Renewable Energies Incorporating BESS and Electrolyzer Degradation

open access: yesIEEE Access
In this study, a large-scale power-to-X (PtX) plant powered by renewable energy (RE) sources for hydrogen (H2) production is modeled with hourly time resolution.
Seyedamin Valedsaravi   +2 more
doaj   +1 more source

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