Results 1 to 10 of about 117,326 (185)

Genome-wide association study of serum tumor markers in Southern Chinese Han population [PDF]

open access: yesBMC Cancer, 2022
Background Serum indicators AFP, CA50, CA125, CA153, CA19-9, CEA, f-PSA, SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide association study on 8 tumor markers of our 427 Han population in southern China, in order to identify ...
Xiukuan Li   +13 more
doaj   +2 more sources

Genetic Variability of TCF4 in Schizophrenia of Southern Chinese Han Population: A Case-Control Study [PDF]

open access: yesFrontiers in Genetics, 2019
Objective: Schizophrenia is thought to be a neurodevelopmental disorder. As a key regulator in the development of the central nervous system, transcription factor 4 (TCF4) has been shown to be involved in the pathogenesis of schizophrenia. The aim of our
Jingwen Yin   +24 more
doaj   +2 more sources

Association of the MMP-9 polymorphism and ischemic stroke risk in southern Chinese Han population [PDF]

open access: yesBMC Neurology, 2019
Background Stroke is a serious cardiovascular disease and is also the leading cause of long-term disability in developing and developed countries. Because matrix metalloproteinase-9 (MMP-9) is associated with the risk of many cardiovascular diseases, we ...
Ning Gao   +6 more
doaj   +2 more sources

Polymorphisms in the Human Aquaporin 4 Gene Are Associated With Schizophrenia in the Southern Chinese Han Population: A Case–Control Study [PDF]

open access: yesFrontiers in Psychiatry, 2020
BackgroundIn psychiatric illness, pathogenic role of neuroinflammation has been supported by multiple lines of evidence. Astrocytes contribute to the blood-brain barrier (BBB) with formation of the “glymphatic” drainage system of the central nervous ...
Yung-Fu Wu   +4 more
doaj   +2 more sources

Association between the PPP1R3B polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke in a southern Chinese Han population [PDF]

open access: yesNutrition & Metabolism, 2018
Background Little is known about the association of the protein phosphatase 1 regulatory subunit 3B gene (PPP1R3B) single nucleotide polymorphisms (SNPs) and serum lipid levels, the risk of coronary artery disease (CAD) and ischemic stroke (IS) in the ...
Wei-Jun Li   +5 more
doaj   +2 more sources

High Level Serum Procalcitonin Associated Gouty Arthritis Susceptibility: From a Southern Chinese Han Population. [PDF]

open access: yesPLoS ONE, 2015
To study the serum Procalcitonin (PCT) level in inflammatory arthritis including gouty arthritis (GA), Rheumatoid arthritis (RA), and ankylosing spondylitis (AS) without any evidence of infection were evaluated the possible discriminative role of PCT in ...
Wen Liu   +8 more
doaj   +2 more sources

Association of MTMR3 rs12537 at miR-181a Binding Site with Ischemic Stroke in Southern Chinese Han Population [PDF]

open access: yesInternational Journal of General Medicine
Linfa Chen,1,2,* Shan Wei,2,* Yutian Zhang,3,* You Li,3 Zishan Li,2 Pengru Huang,1 Chun Xiao,2 Yusheng Zhang1 1Department of Neurology, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, People’s Republic of ...
Chen L   +7 more
doaj   +2 more sources

Serum Cytokines Th1, Th2, and Th17 Expression Profiling in Active Lupus Nephritis-IV: From a Southern Chinese Han Population [PDF]

open access: yesMediators of Inflammation, 2016
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by aberrant T cell immune response. Diffuse proliferative lupus nephritis (LN-IV) is the most common, severe, and active form of lupus nephritis.
Keshav Raj Sigdel   +11 more
doaj   +2 more sources

Patrilineages of ethnolinguistically diverse populations reveal multifactorial influences on Chinese paternal population stratification [PDF]

open access: yesBMC Biology
Background Large-scale Y-chromosome genetic resources provide critical insights into human evolutionary history. However, the limited high-density Y-chromosomal data from ethnolinguistically diverse Chinese populations hinder the reconstruction of fine ...
Ting Yang   +11 more
doaj   +2 more sources

Genomic formation of lower Yellow River populations in the Han dynasty [PDF]

open access: yesBMC Biology
Background As a key region in the lower Yellow River Basin, Shandong Province plays a central role in understanding the genetic history of East Asia. However, detailed ancient DNA data across its historical periods remains limited.
Zhi Ji   +28 more
doaj   +2 more sources

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