Mitochondrial DNA Polymorphism in Zhejiang She Population Based on Next Generation Sequencing [PDF]
Objective To study the genetic polymorphism of whole mitochondrial DNA (mtDNA) genomes in She population in Zhejiang and to explore the maternal genetic structure of the She population.
YANG Qi, ZHANG Jing-yi, ZHANG Xiao-chun, et al.
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Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. [PDF]
BackgroundHuman leukocyte antigen DP (HLA-DP) locus has been reported to be associated with hepatitis B virus (HBV) infection in populations of Japan and Thailand.
Jin Li +23 more
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Ancient DNA reveals that the genetic structure of the northern Han Chinese was shaped prior to 3,000 years ago. [PDF]
The Han Chinese are the largest ethnic group in the world, and their origins, development, and expansion are complex. Many genetic studies have shown that Han Chinese can be divided into two distinct groups: northern Han Chinese and southern Han Chinese.
Yong-Bin Zhao +8 more
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Genomic insight into the population history of Central Han Chinese
Background In recent decades, considerable attention has been paid to exploring the population genetic characteristics of Han Chinese, mainly documenting a north-south genetic substructure.
Xiaomin Yang +11 more
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Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese [PDF]
Background: Genome-wide association studies (GWAS) in Caucasians have identified fourteen index single nucleotide polymorphisms (iSNPs) that influence colorectal cancer (CRC) risk.
Amanda Ewart Toland +9 more
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Hypospadias is one of the most common congenital external genital malformations, which is characterized by abnormal urethral meatus. However, the etiology remains to be incompletely understood.
Yanqing Liu +8 more
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Evaluating the Association of Eight Polymorphisms with Cancer Susceptibility in a Han Chinese Population. [PDF]
The identification of susceptibility genes for specific types of cancer can provide necessary information for the complete characterization of cancer syndromes.
Ying Dong +6 more
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Modern East Asians derived from the admixture of aborigines and incoming farmers expanding from Yellow and Yangtze River Basins. Distinct genetic differentiation and subsequent admixture between Northeast Asians and Southeast Asians subsequently ...
Pengyu Chen +16 more
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Prior studies have examined the influence of MTHFR C677T on autism susceptibility, however, there are no consensus conclusions and specific analyses of a Chinese population.
Chen-Xi Li +6 more
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Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosus [PDF]
INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease affecting predominantly females. To discover additional genetic risk variants for SLE on the X chromosome, we performed a follow-up study of our previously ...
Bei, JX +30 more
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