Results 61 to 70 of about 117,326 (185)

Effect of SYTL3-SLC22A3 Variants, Their Haplotypes, and G × E Interactions on Serum Lipid Levels and the Risk of Coronary Artery Disease and Ischaemic Stroke

Frontiers in Cardiovascular Medicine, 2021
Background: The current study aimed to investigate the effects of synaptotagmin-like 3 (SYTL3) and solute carrier family 22 member 3 (SLC22A3) single nucleotide polymorphisms (SNPs) and gene-environment (G × E) interactions on blood lipid levels as well ...
Peng-Fei Zheng, Rui-Xing Yin, Xiao-Li Cao, Wu-Xian Chen, Jin-Zhen Wu, Feng Huang   +5 more
doaj   +1 more source

The Beixin Culture archaeobotanical evidence from Guanqiaocunnan indicates a population dispersal of hunter-gatherercultivators into and across the Haida region of northern China [PDF]

, 2020
The Beixin Culture appears within the hilly southwestern area of the Haidai region of northern China at ca. 5000 BC, and spreads to its north and northeast flood plains in the following millennium, replacing the Houli Culture.
Bellwood, Bellwood, Cai, Chen, Crowther, Fuller, Guo, Habu, Han, Jin, Li, Liu, Long, Luan, Luan, Mithen, Pursglove, Qiang, Qin, Rao, Reich, Shi, Shoda, Song, Stevens, Wang, Wang, Wang, Wen, Wu, Zhang, Zhao, Zheng, Zou   +33 more
core   +2 more sources

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population. [PDF]

PLoS ONE, 2015
The first genome-wide association study for coronary artery disease (CAD) in the Han Chinese population, we reported recently, had identified rs6903956 in gene ADTRP on chromosome 6p24.1 as a novel susceptibility locus for CAD.
Er-Wen Huang, Long-Yun Peng, Jin-Xiang Zheng, Dan Wang, Qu-Yi Xu, Lei Huang, Qiu-Ping Wu, Shuang-Bo Tang, Bin Luo, Shui-Ping Liu, Xiao-Shan Liu, Zhao-Hui Li, Li Quan, Yue Li, He Shi, Guo-Li Lv, Jian Zhao, Jian-Ding Cheng, Chao Liu   +18 more
doaj   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations

BMC Biology
Background The underrepresentation of human genomic resources from Southern Chinese populations limited their health equality in the precision medicine era and complete understanding of their genetic formation, admixture, and adaptive features.
Qiuxia Sun, Mengge Wang, Tao Lu, Shuhan Duan, Yan Liu, Jing Chen, Zhiyong Wang, Yuntao Sun, Xiangping Li, Shaomei Wang, Liuyi Lu, Liping Hu, Libing Yun, Junbao Yang, Jiangwei Yan, Shengjie Nie, Yanfeng Zhu, Gang Chen, Chuan-Chao Wang, Chao Liu, Guanglin He, Renkuan Tang   +21 more
doaj   +1 more source

Using local ecological knowledge to assess the status of the Critically Endangered Chinese giant salamander Andrias davidianus in Guizhou Province, China [PDF]

, 2015
The Critically Endangered Chinese giant salamander Andrias davidianus, the world's largest amphibian, is severely threatened by unsustainable exploitation of wild individuals.
Chen, Shu, Cunningham, Andrew A., Li, Shize, Milner-Gulland, E. J., Pan, Yuan, Turvey, Samuel T., Wei, Gang   +6 more
core   +3 more sources

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

Advanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu, Mengyao Zhang, Zitong Qiu, Xinyi Liu, Yunsheng Dou, Sona Krizkova, Zheyi Li, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Association between CYP2B6 polymorphism and acute leukemia in a Han population of Northwest China

Molecular Genetics & Genomic Medicine, 2020
Background The aim of this study was to investigate potential associations between CYP2B6 c.516G>T polymorphism and the occurrence and prognosis of acute leukemias (AL) in the Han population of Northwest China.
Li‐Li Yu, Wei Zhang, Juan Li, Li Zhao
doaj   +1 more source