Results 61 to 70 of about 117,969 (248)

Exploring Y-chromosomal STRs and SNPs for forensic and genetic insights in the Jiangsu Han population

BMC Genomics
Y-chromosome short tandem repeats (Y-STRs) and single nucleotide polymorphisms (Y-SNPs) are valuable genetic markers used for individual identification, forensic applications, and the study of paternal lineage history.
Min Li, Han Zhang, Ruiyang Tao, Anqi Chen, Peng Zhou, Chunjiang Yu, Yingnan Bian, Suhua Zhang, Chen Fang, Chengtao Li   +9 more
doaj   +1 more source

Effect of SYTL3-SLC22A3 Variants, Their Haplotypes, and G × E Interactions on Serum Lipid Levels and the Risk of Coronary Artery Disease and Ischaemic Stroke

Frontiers in Cardiovascular Medicine, 2021
Background: The current study aimed to investigate the effects of synaptotagmin-like 3 (SYTL3) and solute carrier family 22 member 3 (SLC22A3) single nucleotide polymorphisms (SNPs) and gene-environment (G × E) interactions on blood lipid levels as well ...
Peng-Fei Zheng, Rui-Xing Yin, Xiao-Li Cao, Wu-Xian Chen, Jin-Zhen Wu, Feng Huang   +5 more
doaj   +1 more source

3D‐Printed Hygroscopic Polymer Networks for High‐Humidity Triboelectric Nanogenerators to Wirelessly Power Implantable Electronic Devices‐ A Conceptual Pathway

Advanced Functional Materials, EarlyView.
This work develops 3D‐printable tribopolymer networks that can enhance triboelectric performance under high humidity environments. Polar hydrophilic functional groups and incorporation of zwitterionic monomers promote bound‐water–dominated interfacial polarization thereby increasing electrical outputs.
Linguangze Zhuo, Jiawang Zeng, Qian Chen, Valentin A. Bobrin, Deepak Mishra, Anthony Chun Yin Yuen, Yixia Zhang, Cyrille Boyer, Jin Zhang   +8 more
wiley   +1 more source

Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population. [PDF]

PLoS ONE, 2015
The first genome-wide association study for coronary artery disease (CAD) in the Han Chinese population, we reported recently, had identified rs6903956 in gene ADTRP on chromosome 6p24.1 as a novel susceptibility locus for CAD.
Er-Wen Huang, Long-Yun Peng, Jin-Xiang Zheng, Dan Wang, Qu-Yi Xu, Lei Huang, Qiu-Ping Wu, Shuang-Bo Tang, Bin Luo, Shui-Ping Liu, Xiao-Shan Liu, Zhao-Hui Li, Li Quan, Yue Li, He Shi, Guo-Li Lv, Jian Zhao, Jian-Ding Cheng, Chao Liu   +18 more
doaj   +1 more source

Inference of population splits and mixtures from genome-wide allele frequency data [PDF]

, 2012
Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In this paper, we present a statistical model for inferring
A Keinan, A RoyChoudhury, AL Price, AR Boyko, BM Henn, BM vonHoldt, BS Weir, C Becquet, D Reich, D Reich, D Reich, DH Huson, DJ Lawson, EY Durand, G Bhatia, G Coop, G Hellenthal, G Liti, G McVean, G Nicholson, GM Lathrop, HG Parker, Hua Tang, I Gronau, J Felsenstein, J Felsenstein, J Felsenstein, J Hey, J Novembre, J Novembre, J Novembre, J Sirén, J Sukumaran, JK Pritchard, JK Pritchard, Jonathan K. Pritchard, Joseph K. Pickrell, JZ Li, K Lindblad-Toh, LL Cavalli-Sforza, LL Cavalli-Sforza, LL Cavalli-Sforza, LL Cavalli-Sforza, LS Kubatko, M Bonhomme, M DeGiorgio, M Jakobsson, M Nei, M Nei, M Rasmussen, MA Beaumont, N Patterson, N Patterson, N Saitou, NA Rosenberg, O François, P Beerli, P Menozzi, P Moorjani, R Nielsen, RE Green, RJ Dyer, RL Cann, RN Gutenkunst, RR Hudson, S Xu, SF Schaffner   +66 more
core   +5 more sources

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations

BMC Biology
Background The underrepresentation of human genomic resources from Southern Chinese populations limited their health equality in the precision medicine era and complete understanding of their genetic formation, admixture, and adaptive features.
Qiuxia Sun, Mengge Wang, Tao Lu, Shuhan Duan, Yan Liu, Jing Chen, Zhiyong Wang, Yuntao Sun, Xiangping Li, Shaomei Wang, Liuyi Lu, Liping Hu, Libing Yun, Junbao Yang, Jiangwei Yan, Shengjie Nie, Yanfeng Zhu, Gang Chen, Chuan-Chao Wang, Chao Liu, Guanglin He, Renkuan Tang   +21 more
doaj   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

Absence of mutations in exon 6 of the TARDBP gene in 207 Chinese patients with sporadic amyotrohic lateral sclerosis. [PDF]

PLoS ONE, 2013
Mutations in the TARDBP gene, which encodes the Tar DNA binding protein, have been shown to causes of both familial amyotrophic lateral sclerosis (FALS) and sporadic ALS (SALS). Recently, several novel TARDBP exon 6 mutants have been reported in patients
Cheng-hui Ye, Xi-lin Lu, Min-ying Zheng, Jun Zhen, Zhi-Ping Li, Lei Shi, Zhi-yong Liu, Lu-yang Feng, Zhong Pei, Xiao-li Yao   +9 more
doaj   +1 more source

China`s xinjiang policy: an analysis based on the theory of relative deprivation [PDF]

, 2011
Xinjiang, which is China’s western province that comprised 18 percent of the country’s total land area and heavily populated by non-Han Chinese ethnic minorities, is a region increasingly beset by the problem of confrontation between two very distinct ...
Nur Shahadah Jamil,
core