Results 21 to 30 of about 89 (68)

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

open access: yesAdvanced Materials, Volume 37, Issue 47, November 27, 2025.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye   +20 more
wiley   +1 more source

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

open access: yesAnnals of Neurology, Volume 98, Issue 5, Page 1027-1043, November 2025.
Objective Blood‐based biomarkers for Alzheimer's disease (AD), representing antemortem indicators of AD pathophysiology, have greatly improved the accuracy of diagnosis. However, these biomarkers may not capture a frequent coincident pathology, such as cerebrovascular disease.
Tamil Iniyan Gunasekaran   +12 more
wiley   +1 more source

Bug roads: Modeling the green space connectivity and pollinator habitat in a large city using open GIS data and tools

open access: yesEcological Applications, Volume 35, Issue 7, October 2025.
Abstract The conservation of native bees and other pollinators is an important consideration for the future of urban sustainability. Parks, urban gardens, cemeteries, and other green spaces can provide habitat space for both native and non‐native pollinators in cities.
Matthew J. Lundquist   +4 more
wiley   +1 more source

Oregon Wolfe barley genetic stocks – Research and teaching tools for next generation scientists

open access: yesJournal of Plant Registrations, Volume 19, Issue 3, September/December 2025.
Abstract The Oregon Wolfe Barley (OWB) mapping population (Reg. no. MP‐4, NSL 554937 MAP) is a resource for genetics research and instruction. The OWBs are a set of doubled haploid barley (Hordeum vulgare L.) lines developed at Oregon State University from the F1 of a cross between Dr. Robert Wolfe's dominant and recessive marker stocks.
Margaret R. Krause   +45 more
wiley   +1 more source

Improved High Resolution Heat Exposure Assessment With Personal Weather Stations and Spatiotemporal Bayesian Models

open access: yesGeoHealth, Volume 9, Issue 9, September 2025.
Abstract Most of the United States (US) population resides in cities, where they are subjected to the urban heat island effect. In this study, we develop a method to estimate hourly air temperatures at 0.01°×0.01° $0.01{}^{\circ}\times 0.01{}^{\circ}$ resolution, improving exposure assessment of US population when compared to existing gridded products.
Eva Marquès, Kyle P. Messier
wiley   +1 more source

Expanding the Non‐Clinical Mental Health Workforce: Protocol for a Randomized Controlled Trial of a Psychological Intervention Delivered by Community‐Based Organizations in New York City (RECOUP‐NY)

open access: yesPsychiatric Research and Clinical Practice, Volume 7, Issue 3, Page 200-212, Autumn (Fall) 2025.
Objective In 2022, half a million residents of New York City reported being unable to access mental health services. One solution to combat this service gap is community‐initiated care (CIC), in which staff, who are not mental health specialists, at community‐based organizations (CBOs) identify clients experiencing distress and then deliver a brief ...
Brandon A. Kohrt   +17 more
wiley   +1 more source

Physics‐Based Spatial Oversampling of TROPOMI NO2 Observations to US Neighborhoods Reveals the Disparities of Air Pollution

open access: yesGeoHealth, Volume 9, Issue 8, August 2025.
Abstract Satellite observations provide continuous and global coverage observations of air pollutants, widely used to inform health impacts and air pollution disparities. Linking satellite retrievals with socioeconomic or health data involves matching the irregularly shaped satellite observations with administrative units.
Xiaomeng Jin, Zaina Merchant, Kang Sun
wiley   +1 more source

2025 ACVIM Forum Research Abstract Program

open access: yes
Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source
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