Results 181 to 190 of about 2,461 (302)

The impact of sovereign credit risk on bank funding conditions

open access: yes
The financial crisis and the ensuing recession have caused a sharp deterioration in public finances across advanced economies, raising investor concerns about sovereign risk.
Marques, José-Manuel   +10 more
core  

COVID-19 and credit risk: A long memory perspective. [PDF]

open access: yesInsur Math Econ, 2022
Yin J, Han B, Wong HY.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Trends of the Contagion Risk in Sovereign Spreads for Emerging European Countries [PDF]

open access: yes
We investigate the sovereign spreads behavior of the European emerging countries using the clustering technique. Our main finding is that the distances between spreads during high volatile times is significantly lower than in normal periods, that is, the
Neagu, Florian   +2 more
core  

BioStruct-Africa's scalable framework for AlphaFold-enabled research training and sustainable workforce development in Africa. [PDF]

open access: yesCommun Biol
Amofa JO   +79 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Bridging emerging market models and investors realities: the case of currency and external debt markets.

open access: yes, 2012
PhDOur target is to objectively quantify important aspects of emerging economies’ financial markets and deliver value adding actionable recommendations that can be used by a wide spectrum of end-users like academics, policy makers and real life ...
Lekka, Nikoletta
core  

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