Results 111 to 120 of about 21,124,301 (247)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Joint blind and semi-blind detection and channel estimation for space-time trellis coded systems [PDF]

, 2003
The paper considers a multiple-input multiple-output (MIMO) communication system, which uses space-time trellis coding (STTC). A novel method of decoding STTC without a need to transmit training sequences is developed.
Nix, AR, Piechocki, RJ, Andrieu, C, McGeehan, JP   +3 more
core  

Symmetric Radial Basis Function Assisted Space-Time Equalisation for Multiple Receive-Antenna Aided Systems

, 2007
This contribution considers nonlinear space-time equalisation (STE) designed for single-input multiple-output (SIMO) systems. By exploiting the inherent symmetry of the underlying optimal Bayesian STE solution, a novel symmetric radial basis function ...
Liu, S., Hanzo, L., Chen, S.
core   +1 more source

Robust Algorithm for Adaptive Processingin Strong Space time Clutter Envirnment

工程科学与技术, 2009
:A novel Quiescent Pattern Control(QPC) approach was proposed for airborne radar weak signal detection in strong space time clutter environment. The new QPC approach imposed quadratic beampattern constraints in the adaptive processing and exploited the ...
doaj  

A novel sparse recovery space‐time adaptive processing algorithm using the log‐sum penalty to approximate the ℓ0 − norm penalty

IET Radar, Sonar & Navigation
Applying the sparse recovery (SR) technique to airborne radar space‐time adaptive processing (STAP) can greatly reduce the number of required training samples, which is advantageous in detecting targets in non‐homogeneous and non‐stationary clutter ...
Kun Liu, Tong Wang
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A Convex Combination Of H2 And H∞ Filters For Space-time Adaptive Equalization

, 2015
In this work, H2 and H optimization criteria are briefly discussed and evaluated in the context of adaptive space-time channel equalization. While the first criterion presents better mean performance, the second one is more appropriate for worst case ...
Abbas-Turki M., Chaves F.D.S., Abou-Kandil H., Romano J.M.T.   +3 more
core   +1 more source

A Fast IAA–Based SR–STAP Method for Airborne Radar

Remote Sensing
Space–time adaptive processing (STAP) is an effective technology in clutter suppression and moving target detection for airborne radar. When working in the heterogeneous environment, the number of training samples that satisfy independent and identically
Shuguang Zhang, Tong Wang, Cheng Liu, Bing Ren   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source