Results 201 to 210 of about 53,480 (290)

Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1‐mediated P53 ubiquitination

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Based on a dermis fibroblast Gorab knockout mouse model, this study revealed that Gorab deficiency promotes skin aging by influencing RCHY1, causing a decrease in P53 ubiquitination, damaging the activity of HDAC2, further resulting in the accumulation of aging‐related proteins (P53, P21, P16) and a reduction in extracellular matrix (ECM) components ...
Yanhong Li   +7 more
wiley   +1 more source

OAM multiplication operator enabled holographic multiplexing. [PDF]

open access: yesLight Sci Appl
Shen F   +8 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen   +8 more
wiley   +1 more source

Dispersive Full-Channel Jones Matrix Modulation in Elliptical Polarization Bases via a Single-Layered Metasurface. [PDF]

open access: yesAdv Sci (Weinh)
He H   +10 more
europepmc   +1 more source

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li   +4 more
wiley   +1 more source

Acoustofluidic Patterning for Improved Microtissue Histology

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh   +13 more
wiley   +1 more source

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