Results 221 to 230 of about 18,710 (282)

Uncovering Hidden Phenotypes in NEX‐Cre Mice: Behavioral and Cellular Alterations Demand Re‐Evaluation of a Widely Used Transgenic Line

open access: yesJournal of Neurochemistry, Volume 170, Issue 3, March 2026.
Cre‐driver mouse lines are widely used for targeted gene manipulation, yet their baseline phenotypes are often assumed to be neutral. Here, we reveal hidden behavioral and synaptic alterations in the commonly used NEX‐Cre line, including changes in locomotion, anxiety‐like behavior, reward‐related behavior, and region‐specific dendritic spine density ...
Kim Renken, Olivia Andrea Masseck
wiley   +1 more source

Spatial Patterns of Intraspecific Genetic Diversity Follow no General Rule Across Climatic and Geographic Gradients

open access: yesMolecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Intraspecific genetic diversity (ISD) underpins key eco‐evolutionary processes, yet its spatial distribution across species' ranges remains poorly understood at broad scales. Combining mitochondrial sequence alignments, species distribution models and comparative analyses, we tested whether populations closer to current niche optima exhibit ...
Matthew O. Moreira   +5 more
wiley   +1 more source

Emotional valence through pupil: Machine learning classification under controlled visual complexity and emotional arousal in young adults

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Abstract Pupillometry has long been proposed as a noninvasive physiological measure for emotional valence. However, its empirical effectiveness remains inconclusive due to confounding visual and emotional factors. This study examined whether pupil response patterns alone can reliably distinguish between positive and negative emotional stimuli while ...
Jung Joo Lee   +3 more
wiley   +1 more source

Assessing head injury risk and neuroprotective effect of ketone monoester supplementation in military airborne training

open access: yesPhysiological Reports, Volume 14, Issue 6, March 2026.
Abstract Warfighters face significant risk of mild traumatic brain injury (mTBI) during operations and training. We performed a double‐blind, randomized, placebo‐controlled trial to: (1) determine head strike (HS) incidence, during US Army Basic Airborne Course's Improved Swing Landing Trainer (ISLT) training, (2) test protective efficacy of ketone ...
Toshiya Miyatsu   +19 more
wiley   +1 more source

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