Results 141 to 150 of about 6,366,300 (284)

NASA Technical Exhibit: Space for the Benefit of Mankind, Seattle World's Fair, 1962

open access: yes, 1962
From the introduction: The National Aeronautics and Space Administration (NASA) is a civilian agency established in 1958 by the Congress of the United States to control and manage the Nation's programs for peaceful aeronautical and space activities ...
National Aeronautics and Space Administration
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Leveraging latent space models for enzyme discovery and sampling. [PDF]

open access: yesProc Natl Acad Sci U S A
Chiang CH   +3 more
europepmc   +1 more source

Review of U.S. Human Space Flight Plans Committee

open access: yes, 2010
This website contains information about the Review of U.S. Human Space Flight Plans Committee including their final report from October 2009. Acourding to their "About" page, "[t]he "Review of United States Human Space Flight Plans" is to examine ...
United States. National Aeronautics and Space Administration. Review of U.S. Human Space Flight Plans Committee.
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Space biology as a catalyst for the next biotech and longevity revolution. [PDF]

open access: yesExp Physiol
Kern C   +21 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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