Results 181 to 190 of about 3,422,349 (365)

Commercial space services [PDF]

open access: yes
An overview of space service opportunities as identified by a Wyle Laboratories' research team is given. Through the use of a baseline space scenario, a variety of space hardware, services, and commercial activities are identified and related on a time ...
Christensen, D. L.
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Combined Social Frailty and Life-Space Activities Associated with Risk of Disability: A Prospective Cohort Study. [PDF]

open access: yesJ Frailty Aging
Doi T   +6 more
europepmc   +1 more source

Research and development activities at the Goddard Space Flight Center for the flight telerobotic servicer project [PDF]

open access: yes
The Flight Telerobotic Servicer (FTS) is being developed by the Goddard Space Flight Center (GSFC) for performing a variety of assembly, servicing, inspection and maintenance tasks on the Space Station.
Ollendorf, Stanford
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Industrializing the near-earth asteroids: Speculations on human activities in space in the latter half of the 21st century [PDF]

open access: yes
The use of solar system resources for human industry can be viewed as a natural extension of the continual growth of our species' habitat. Motivations for human activities in space can be discussed in terms of five distinct areas: (1) information ...
Sercel, Joel C.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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