Results 221 to 230 of about 3,422,349 (365)

Associations between access to green and blue spaces and physical activity attainment – an 18-country study

, 2019
Lewis R. Elliott, Mathew P. White, James Grellier, Benedict W. Wheeler, Joanne K. Garrett, Marta Cirach, Mireia Gascón, Gregory N. Bratman, van den Bosch M, Ann Ojala, Anne Roiko, Á. O’Connor, Maria Luı́sa Lima, Mark Nieuwenhuijsen, Lora E. Fleming   +14 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Multi-criteria spatial assessment of urban open spaces for promoting physical activity and spatial justice: a case study of Tehran metropolitan. [PDF]

Sci Rep
Javid M, Taheri Z, Goodarzi S, Saberi A, Shorabeh SN, Firozjaei MK, Arsanjani JJ.   +6 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Italian Space Agency - Space Debris Mitigation Activities - Delegation Presentation

, 2012
Space debris mitigation activities carried out in Italy between IADC-32 and IADC-33 (April 2014 - March 2015). Status of satellite launches, reentries, collision avoidance and end of life disposal.
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Association between social support and life space mobility in older patients after percutaneous coronary intervention: mediating roles of health literacy and intrinsic capacity. [PDF]

Front Public Health
Dan Y, Li Q, Xu T, Tu X, Yan L.
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Grounded in culture: a participatory empowerment evaluation of the oskâyak (youth) power program for oskinîkiwak (young men) and napêsisak (boys) at pakitahaw sākahikan iýiniwak (sturgeon lake first nation). [PDF]

Int J Circumpolar Health
Rabbitskin N, Ballantyne C, Okpalauwaekwe U, Tunison S, Ramsden VR.   +4 more
europepmc   +1 more source