Results 21 to 30 of about 3,656,515 (237)

THE INFLUENCE OF ‘GANG BARU’ TRADITIONAL MARKET ACTIVITIES IN THE USE OF PUBLIC SPACE IN SEMARANG CHINATOWN [PDF]

open access: yes, 2016
Chinatown is one of the commercial district in Semarang city, which continues to grow in the city center. It’s a 'generator' that drives a wide variety of economic activities, also self-actualization and disclosure of aspiration, expression of the people.
Fiton Dwi, Setiawan, Rina, Kurniati
core  

Interaction patterns of brain activity across space, time and frequency. Part I: methods [PDF]

open access: yes, 2011
We consider exploratory methods for the discovery of cortical functional connectivity. Typically, data for the i-th subject (i=1...NS) is represented as an NVxNT matrix Xi, corresponding to brain activity sampled at NT moments in time from NV cortical ...
Biscay-Lirio, Rolando J.   +1 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Automated Selection of Active Orbital Spaces [PDF]

open access: yesJournal of Chemical Theory and Computation, 2016
29 pages, 10 figures, 5 ...
Stein Christopher J., Reiher Markus
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Increasing Active Living: A Guide for Policy-Makers [PDF]

open access: yes, 2007
Outlines how street layout, zoning, recreation facilities, and public building locations shape residents' physical activity. Suggests state and local policies on planning, land use, transportation, and space design to create activity-friendly ...

core  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Suited for spacewalking: A teacher's guide with activities [PDF]

open access: yes, 1992
This publication is an activity guide for teachers on spacesuits and spacewalking. It uses the intensive interest many children have in space exploration as a launching point for hands-on-opportunities.
Manning, Cheryl A., Vogt, Gregory L.
core   +1 more source

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