Results 41 to 50 of about 7,607,101 (286)

Interpretation of transverse tune spectra in a heavy-ion synchrotron at high intensities

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2013
Two different tune measurement systems have been installed in the GSI Helmholtzzentrum für Schwerionenforschung heavy-ion synchrotron SIS-18. Tune spectra are obtained with high accuracy using these fast and sensitive systems.
R. Singh   +8 more
doaj   +1 more source

Space charge and trap energy level characteristics of SiC wide bandgap semiconductor

open access: yesAIP Advances, 2022
Charge carrier transport and accumulation in silicon carbide (SiC) wide bandgap semiconductors caused by the defect and impurity are likely to lead to serious performance degradation and failure of the semiconductor materials, and the high temperature ...
Chi Chen   +6 more
doaj   +1 more source

Study on the effect of proton irradiation on the dose response of RADFETs to γ-ray

open access: yesHe jishu, 2022
BackgroundRadiation sensitive field-effect transistors (RADFETs) are calibrated on the ground using a 60Co γ-ray source that is different from the proton-electron radiation environment that exists in actual space applications.PurposeThis study aims to ...
MA Han   +3 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Space charge measurement and analysis in low density polyethylene films

open access: yes, 2009
The growing requirement of reliability for an insulation system gives researchers greater responsibility to investigate new techniques for monitoring and diagnosing dielectrics subjected to an electric field.
Xu, Zhiqiang
core   +1 more source

Measurement of space charge effect on transverse emittance [PDF]

open access: yesPACS2001. Proceedings of the 2001 Particle Accelerator Conference (Cat. No.01CH37268), 2002
The SNS accumulator ring is designed to compress 1.5/spl times/10/sup 14/ 1 GeV protons from a bunch train of 1000 /spl mu/s H/sup -/ to a single proton bunch with bunch length 700 ns. The injection scenario of the SNS is experimentally simulated at the Cooler Injector Synchrotron (CIS) at Indiana University. A 100 /spl mu/s, 7 MeV H/sup -/ bunch train
S. Cousineau   +15 more
openaire   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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