Results 31 to 40 of about 100,835 (255)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Narrow line cooling and momentum-space crystals [PDF]

open access: yesPhysical Review A, 2004
Narrow line laser cooling is advancing the frontier for experiments ranging from studies of fundamental atomic physics to high precision optical frequency standards. In this paper, we present an extensive description of the systems and techniques necessary to realize 689 nm 1S0 - 3P1 narrow line cooling of atomic 88Sr.
Loftus, Thomas H.   +4 more
openaire   +2 more sources

EXPERIMENTS ON ELECTRON COOLING AND INTENSE SPACE-CHARGE AT IOTA

open access: yesCOOL'23 Conference, Montreux, Switzerland, October 8, 2023, 2023
14th International Workshop on Beam Cooling and Related Topics (COOL'23)
Banerjee, N.   +5 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Design of Double‐Sided Optical Coatings for Space Cooling Through Vertical Windows

open access: yesAdvanced Photonics Research
Passive radiative cooling is a promising energy‐saving strategy for space cooling. Dual‐sided thermal emitters offer efficient heat removal from enclosed spaces; however, existing studies predominantly focus on rooftop applications, with limited ...
Hyunkyu Kwak   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effects of Supply Angle on Thermal Environment of Residential Space with Hybrid Desiccant Cooling System for Multi-Room Control

open access: yesApplied Sciences, 2020
In this study, local measurement and computational fluid dynamics (CFD) were employed to evaluate the thermal comfort in a residential environment where desiccant cooling is performed in an outdoor air condition, which is the typical summer weather in ...
Joon Ahn, Ho Yup Choi
doaj   +1 more source

MICE: The International muon ionization cooling experiment: Phase space cooling measurement [PDF]

open access: yes2007 IEEE Particle Accelerator Conference (PAC), 2007
MICE is an experiment with a section of an ionization cooling channel and a muon beam. The muons will be produced by the decay of pions from a target dipping into the ISIS proton beam at Rutherford Appleton Laboratory (RAL). The channel includes liquid-hydrogen absorbers providing transverse and longitudinal momentum loss and high-gradient ...
T. L. Hart   +3 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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