Results 41 to 50 of about 4,109,239 (244)

Hybrid-Compliant System for Soft Capture of Uncooperative Space Debris [PDF]

open access: yes, 2023
peer reviewedActive debris removal (ADR) is positioned by space agencies as an in-orbit task of great importance for stabilizing the exponential growth of space debris.
HUBERT DELISLE, Maxime   +11 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

An axiomatic system engineering design method based on NSGA-II algorithm applied to complex systems

open access: yesScientific Reports
This study proposes an integrated framework that combines Axiomatic Design with Model-Based Systems Engineering, incorporating NSGA-II as an intelligent optimization engine. The framework constructs a multi-level traceability matrix linking requirements,
Xiaoqian Zhang   +7 more
doaj   +1 more source

STar-DETR: A Lightweight Real-Time Detection Transformer for Space Targets in Optical Sensor Systems

open access: yesSensors
Optical sensor systems are essential for space target detection. However, previous studies have prioritized detection accuracy over model efficiency, limiting their deployment on resource-constrained sensors.
Yao Xiao   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Autonomy for Active Space Debris Removal: Research Issues and Approaches [PDF]

open access: yes, 2013
Even though the infinite vastness of the universe is an accepted theory, apparently infinity ends when it comes to orbits surrounding the Earth. This was a hard lesson to learn when Iridium 33 and Cosmos 2251 collided in the low Earth orbit in February ...
Förstner, Roger   +2 more
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Debris mitigation in geostationary earth orbit [PDF]

open access: yes, 2004
Paper presented at Dynamics and Control of Systems and Structures in Space (DCSSS), 6th conference, Riomaggiore, Italy, July 2004The Inter-Agency Debris Committee recommendation for the reorbiting of geostationary satellites at the end of life ...
Todd, Laura, Bowling, Tom
core   +4 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

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