Results 21 to 30 of about 5,976,031 (294)

Rola jednostek samorządu terytorialnego w budowaniu potencjału obszarów metropolitalnych w zakresie promocji zdrowia

open access: yesSpace, Society, Economy, 2023
Metropolia lub obszar metropolitalny jako forma rozwoju społeczno- -gospodarczego stanowi miejsce kumulacji potencjałów ludzkich, finansowych i organizacyjnych, które mogą przyczyniać się do poprawy wskaźników zdrowotnych populacji.
Karolina Sobczyk   +2 more
doaj   +1 more source

Examining Factors Influencing the Occurrence and Intensification of Economic Crises in Iran [PDF]

open access: yesکاوش‌های جغرافیایی مناطق بیابانی
Extended Abstract1. IntroductionThe spatial distribution and operating locations of an economy’s components, along with the spatial flow of goods and population, are referred to as the space economy.
Reza Amiri   +2 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

[Presentation] Space and the Circular Economy: Exploring Expert Perceptions [PDF]

open access: yes
Space is facing significant sustainability issues such as space debris generation, light pollution, green-house gas emissions, and ozone layer depletion due to congestion of orbits, increase in rocket launches, and future mega constellations.
BAHLMANN, Jonas   +4 more
core   +1 more source

Initial Measures of the Economic Activity Linked to Bangladesh’s Ocean Space, and Implications for the Country’s Blue Economy Policy Objectives [PDF]

open access: yes, 2019
The Government of Bangladesh resolved its maritime boundaries in 2014, resulting in jurisdiction over ocean space equivalent to 80 percent of the country’s terrestrial area.
Tibor Veigh   +11 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Innovative processes impact on the factors optimal number formation of the enterprise location [PDF]

open access: yesMarketing i Menedžment Innovacij, 2014
The aim of the article. Determination of the factors to locate enterprises for searching optimal location place, therefore grounding enterprise location place with one or several factors one should consider innovative development nowadays.
Franiv Ihor Andriiovych
doaj  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Distributed networked localization using neighboring distances only through a computational topology control approach

open access: yesInternational Journal of Distributed Sensor Networks, 2020
For large-scale wireless sensor networks, the nonlinear localization problem where only neighboring distances are available to each individual sensor nodes have been attracting great research attention. In general, distributed algorithms for this problem
Xiaochu Wang   +3 more
doaj   +1 more source

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