Results 231 to 240 of about 5,289,200 (291)

Chemical Space Exploration and Machine Learning-Based Screening of PDE7A Inhibitors. [PDF]

Pharmaceuticals (Basel)
Li Y, Wang Z, Ma S, Tang X, Zhang H.
europepmc   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Dermatologic Considerations for Spaceflight and Space Exploration. [PDF]

JID Innov
Zhao M, Aintablian H, Satcher RL, Daneshjou R, Rosenbach M.   +4 more
europepmc   +1 more source

Automated Hand Flexor Tendon–Thickness Measurement in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) can affect flexor tendons, contributing to hand function problems and reduced quality of life. Tendon changes are currently assessed with ultrasonography and measured manually, a time‐consuming process prone to interobserver variability.
Mark Greveling, Ties van het Erve, Yvette van de Berg, Simon Mastbergen, Julia Spierings   +4 more
wiley   +1 more source

Parallel synthesis of 5'-amino-5'-deoxy-adenosine derivatives for focused chemical space exploration and their application as methyltransferase inhibitors. [PDF]

RSC Med Chem
Hoba SN, Schwickert M, Kammerer L, Sabin M, Weldert AC, Nidoieva Z, Meidner JL, Barthels F, Schirmeister T, Kersten C.   +9 more
europepmc   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

Arthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

STELLA provides a drug design framework enabling extensive fragment-level chemical space exploration and balanced multi-parameter optimization. [PDF]

Sci Rep
Jeon H, Lee JG, Shin W, Ji H, Joung I, Lee HS.   +5 more
europepmc   +1 more source

Potential Health Impacts, Treatments, and Countermeasures of Martian Dust on Future Human Space Exploration. [PDF]

Geohealth
Wang JL, Rosenbaum JJ, Prasad AN, Raad RR, Putman EJ, Harrington AD, Aintablian H, Hynek BM.   +7 more
europepmc   +1 more source

Correction: To Mars and beyond. Space exploration and space medicine in Leukemia. [PDF]

Leukemia
Gale RP, Hochhaus A.
europepmc   +1 more source

To Mars and beyond. Space exploration and space medicine in Leukemia. [PDF]

Leukemia
Gale RP, Hochhaus A.
europepmc   +1 more source