Results 261 to 270 of about 1,532,844 (348)

Control System Architectures, Technologies, and Concepts for Near Term and Future Human Exploration of Space [PDF]

, 2004
Richard Boulanger, David Overland
openalex   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Wound-healing and onboard care during long-duration human deep space exploration from a surgical perspective through the lens of a scoping review. [PDF]

J Vasc Surg Venous Lymphat Disord
Babocs D, Korrapati K, Lytle C, Gloviczki ML, Oderich GS, Melin MM, Christiansen R.   +6 more
europepmc   +1 more source

How advances in low-g plumbing enable space exploration. [PDF]

NPJ Microgravity, 2022
Weislogel MM, Graf JC, Wollman AP, Turner CC, Cardin KJT, Torres LJ, Goodman JE, Buchli JC.   +7 more
europepmc   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

Synergizing Attribute-Guided Latent Space Exploration (AGLSE) with Classical Molecular Simulations to Design Potent Pep-Magnet Peptide Inhibitors to Abrogate SARS-CoV-2 Host Cell Entry. [PDF]

Viruses
Ullah F, Xiao A, Ullah S, Yang N, Lei M, Chen L, Wang S.   +6 more
europepmc   +1 more source

Mission-critical tasks for assessing risks from vestibular and sensorimotor adaptation during space exploration. [PDF]

Front Physiol, 2022
Clément G, Moudy SC, Macaulay TR, Bishop MO, Wood SJ.   +4 more
europepmc   +1 more source

Integrating self testability with design space exploration by a controller based estimation technique [PDF]

, 2004
Manoj Singh Gaur, Mark Zwoliński
openalex   +1 more source

In-Situ Calorimetric Measurements for Space Exploration [PDF]

, 2005
Barmatz, M., Chui, Talso, Hays, Charles, Hollen, Shawna M.   +3 more
core   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source