Results 251 to 260 of about 80,869 (314)

Hosts and Commensal Bacteria Synergistically Antagonize Opportunistic Pathogens at the Single‐Cell Resolution

Advanced Science, EarlyView.
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang, Ziguang Wang, Anqi Liu, Jinshu Li, Jingjing Zhuang, Xiaowen Ji, Paul I. Mulama, Maoye Li, Haiqun Cao, Eng‐King Tan, Wei Liu   +10 more
wiley   +1 more source

Electronic Microenvironment Regulation of Bismuth‐salophen Single‐site Catalysts for Enhanced Selectivity in CO2 Electrolysis to Formic Acid

Advanced Science, EarlyView.
The microenvironment modulation of Bi SSCs via electronegative group (─F/─H/─OMe) modification demonstrably suppresses the HER at high current densities, achieving a HCOOH FE of 95%. The ─F group optimizes the electronic structure of Bi, significantly enhancing CO2 adsorption and reducing the energy barrier for *OCHO intermediate formation, thereby ...
Tianxing Wang, Tian (Leo) Jin, Zhiping Liu, Jingtao Wang, Yue Gong, Ming Ma, Jie Chen, Shaohua Shen, Rongqian Wu, Yu‐Cheng Huang, Ying Rui Lu, Yi Lyu, Xiaofei Liu   +12 more
wiley   +1 more source

Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints

Advanced Science, EarlyView.
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao, Guangzhe Liu, Rongjing Zhang, Junhua Yuan   +3 more
wiley   +1 more source

A Full‐Range Proximity‐Tactile Sensor Based on Multimodal Perception Fusion for Minimally Invasive Surgical Robots

Advanced Science, EarlyView.
A full‐range proximity‐tactile sensing module is developed for safe operation of surgical robots, which performs multimodal fusion perception through ultrasonic sensor for long‐range proximity detection, capacitive sensor for close‐range proximity sensing, and triboelectric sensor for tactile sensing.
Dongsheng Li, Tianci Ji, Yuyang Sun, Zhongbin Zhang, Aomen Li, Mengjiao Qu, Dongze Lv, Jin Xie, Huicong Liu   +8 more
wiley   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks

Advanced Science, EarlyView.
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai, Yujie Song, Tuoshi Qi, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuedong Yang, Yuansong Zeng   +7 more
wiley   +1 more source

Proton Acceleration with Relativistic Electromagnetic Shock

Advanced Science, EarlyView.
New Ion Acceleration Mechanism! A novel cosmic‐ray proton acceleration mechanism is proposed, where relativistic electromagnetic shocks accelerate protons transversely. Hamiltonian analysis yields a scaling law linking the proton energy to the minimum longitudinal thickness of the shock.
Ting Xiao, Xiaomei Zhang, Fanqiu Kong, Xiaolong Zheng, Zheng Gong, Baifei Shen   +5 more
wiley   +1 more source

Association of Space Flight With Problems of the Brain and Eyes.

JAMA Ophthalmol, 2018
Shinojima A, Kakeya I, Tada S.
europepmc   +1 more source