Results 241 to 250 of about 1,360,315 (307)

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu, Igor Koop, Gavin Murugan, Thagshanen Thillairajah, Karen M. Polizzi   +4 more
wiley   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Not quite yet: Stakeholder perspectives on health economic evidence use in Non- Communicable Disease priority setting in Kenya

Oguta JO, Wambiya E, Breeze P, Akparibo R, Akoth C, Toweet SK, Mbuthia G, Nyakundi C, Okemwa S, Adjagba A, Dodd PJ.   +10 more
europepmc   +1 more source

One Health for all: Implementing international frameworks with local communities. [PDF]

PLOS Glob Public Health
Ruwet M, Rourke M, Afsana K, Ahamad F, Borja E, Lee K, Wenham C, Woyengu N, Davies SE.   +8 more
europepmc   +1 more source

Rhizospheric traits and plant functioning belowground. [PDF]

Plant Commun
Zhang P, Ding J, Kong D, Yin H.
europepmc   +1 more source

Toward a relational biodiversity economics: Embedding plural values for sustainability transformation. [PDF]

Proc Natl Acad Sci U S A
Kenter JO, Carmenta R, Christie M, Griffiths H, Ihemezie E, Martin A, Gomez-Osorio MT, Pascual U, Raymond CM, Remoundou K, Waters R.   +10 more
europepmc   +1 more source

Tree age affects key fine root morphological traits but does not interfere strongly with (ecto-)mycorrhizal traits. [PDF]

Ann Bot
Qin Y, Valverde-Barrantes OJ, Jin G, Liu Z, Freschet GT.   +4 more
europepmc   +1 more source

Spatial networks of China's specialized, refined, distinctive, and innovative medical device firms based on parent-subsidiary contacts: implications for regional health policy. [PDF]

Front Public Health
Hu F, Yang H, Wei S, Hu H, Chen Y, Zhou H.   +5 more
europepmc   +1 more source

A call to action: impact of climate change on TB and recovery after TB. [PDF]

IJTLD Open
Mabhula A, Hoddinott G, Sohn H, Wright CY, Evans D.   +4 more
europepmc   +1 more source