Results 101 to 110 of about 13,562 (272)

Mantenidors d'espai [PDF]

open access: yes, 2014
Treball Final de Grau d'Odontologia, Facultat d'Odontologia, Universitat de Barcelona, Any: 2014, Director: Marta Nosàs GarciaL’ús d’aparells mantenidors d’espai està enfocat a reduir les conseqüències de la pèrdua prematura d’una dent temporal ...
Farrés Serinyà, Laia
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Biodegradation of nickel and chromium from space maintainers: An in vitro study

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2010
Band materials are often used in the practice of pediatric dentistry. Nickel and Chromium are the main ingredients of these materials. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than ...
Bhaskar V, Subba Reddy V
doaj  

A randomized clinical trial comparing the acceptance of conventional and prefabricated band and loop space maintainers in children with premature loss of primary molar

open access: yesIndian Journal of Dental Research
Objectives: To evaluate and compare the acceptance, comfort, chairside time, and clinical outcomes of conventional and prefabricated band and loop space maintainers in children with premature loss of primary molars. Methods: Sixty children aged 4–8 years
Hem Lata
doaj   +1 more source

Esthetic rehabilitation for premature loss of primary anterior teeth

open access: yesSRM Journal of Research in Dental Sciences, 2019
Over years primary anterior teeth have been prematurely lost due to Early Childhood Caries and trauma. While in the past once lost primary teeth could not be replaced, now due to increased aesthetic demands of the patient and their family, different ...
Paridhee Jalan   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

SimCode: Agent-based Simulation Modelling of Open-Source Software Development [PDF]

open access: yes
We present an original modeling tool, which can be used to study the mechanisms by which free/libre and open source software developers’ code-writing efforts are allocated within open source projects.
Jean-Michel Dalle, Paul A. David
core  

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