Results 61 to 70 of about 13,562 (272)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Clinical evaluation of Fiber Reinforced Composite resin(FRC) as a space maintainer [PDF]

open access: yesIranian Journal of Orthodontics, 2007
Aim: The premature loss of primary molars and the failure to protect this site during normal growth and developmental events may put the normal occurrence of occlusion at risk in the permanent dentition.
Bahman Seraj   +2 more
doaj   +1 more source

DIGITAL SPACE MAINTAINERS

open access: yesInternational Journal of Advanced Research
3D printing is a manufacturing process in which formation of an object is done by building it layer by layer. Many new developments have occurred in paediatric dentistry in recent years. As the world is advancing technologically day by day, 3-D printing technology will be the need of the hour in coming days.
Apurva Chadha   +5 more
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Architecture, design and source code comparison of ns-2 and ns-3 network simulators [PDF]

open access: yes, 2010
Ns-2 and its successor ns-3 are discrete-event simulators. Ns- 3 is still under development, but offers some interesting characteristics for developers while ns-2 still has a big user base.
Amaya Rodríguez, Claudio Antonio   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clinical performance of 3D-printed space maintainers: A systematic appraisal of literature

open access: yesIndian Journal of Dental Research
Objectives: This systematic review aimed to evaluate the clinical performance, advantages, and limitations of 3D-printed space maintainers used in pediatric dentistry.
Mohammad Kamran Khan   +2 more
doaj   +1 more source

A QFD framework for quality, innovation and high-tech product development dynamics [PDF]

open access: yes, 2010
The customer mostly chooses a product on the base of its quality, which therefore arises as the main cause of its commercial success. In a nearly axiomatic drawing, it follows that the effect of innovation is the improvement of quality, which itself ...
Demartini, Claudio Giovanni   +2 more
core  

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