Results 121 to 130 of about 166,276,517 (302)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Interpolation by Earl’s method in the space of functions of semiformal order

open access: yesСовременная математика: Фундаментальные направления
We consider the problem of simple free interpolation in the space of functions of finite order and normal type in a half-plane. We propose its solution by the method of shifting interpolation nodes. This solution is based on Earl’s method, who solved the
M. V. Kabanko, K. G. Malyutin
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bases and isomorphisms in spaces of analytic functions [PDF]

open access: yes, 2006
We will discuss the construction of bases in a space of analytic functions for a given domain and isomorphic classification of spaces of analytic functions. We will focus on results in one dimensional case.
Özal, Zeynep Sıdıka
core   +1 more source

Krein spaces of analytic functions

open access: yesJournal of Functional Analysis, 1988
An inner product space C is called a Krein space in case it is the orthogonal sum of a Hilbert space \(C_+\) and the anti-space \(C_-\) of another Hilbert space (in which the new inner product is the negative of the original one). The Pontryagin index of C is defined to be the dimension of \(C_-\).
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Subordination Results for Classes of Functions of Reciprocal Order

open access: yes, 2016
[[abstract]]In this paper, we introduce the subclassesM^(-1)(α), N^(-1)(α), (M^∗)^(-1)(α) and (N^∗)^(-1)(α) of analytic functions of reciprocal order α.
B.A. Frasin, Y. Talafha, Tariq Al-Hawary
core  

Space is the machine: a configurational theory of architecture [PDF]

open access: yes, 2007
Since The social logic of space was published in 1984, Bill Hillier and his colleagues at University College London have been conducting research on how space features in the form and functioning of buildings and cities. A key outcome is the concept of â€
Hillier, B, Hillier, Bill
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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