Results 201 to 210 of about 8,510,987 (302)
Advanced Science, EarlyView.Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source
Occlusion-Aware Visibility Coverage for Robotic Stop-and-Scan 3D LiDAR Mapping. [PDF]
Sensors (Basel)Kim S, Song Y, Kim B, Kuc TY.
europepmc +1 more source
Advanced Science, EarlyView.Field‐driven active colloids are framed as distributed micromachines in which externally supplied power, sensing, and control regulate task‐relevant states. By closing the loop between particle behavior, imaging, computation, and electric or magnetic actuation, these systems can progress from programmable motion toward adaptive functional outcomes ...
Ruchi Patel, Bhuvnesh Bharti
wiley +1 more source
Modeling the Interplay of Time, Space, Users, Topics, and Sentiment: A Novel Analytical Framework for Social Media Data Analysis. [PDF]
Behav Sci (Basel)Gui W, Dong X, Wang C, Chen S, Zhang W.
europepmc +1 more source
Advanced Science, EarlyView.A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao +7 more
wiley +1 more source
Bio-Inspired CPG Modulation via Proprioceptive Deep Reinforcement Learning for Adaptive Hexapod Locomotion Across Terrain Transitions. [PDF]
Biomimetics (Basel)Jiang H, Lin Y, Li Z, Shuai L.
europepmc +1 more source
An Integrated Artificial Intelligence Framework for Nanomedicine Engineering
Advanced Science, EarlyView.This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong +10 more
wiley +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Optimization of glucocorticoid administration in patients with sepsis using reinforcement learning: a multicenter retrospective study. [PDF]
Front Cell Infect MicrobiolZhang Y, Liang L, Zhang X, Zhao Y.
europepmc +1 more source
Advanced Science, EarlyView.This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui +4 more
wiley +1 more source