Results 121 to 130 of about 1,961,254 (314)

Research on the Cultural Tracing of the Patriarchal Clan System of Traditional Buildings in the Eastern Zhejiang Province, China, Based on Space Syntax: The Case Study of Huzhai in Shaoxing [PDF]

, 2022
Xiaoxiao Rao, Junda Zhou, Kangle Ding, Jifeng Wang, Jiaqi Fu, Qinghong Zhu   +5 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Research on the Application of Blank Space Technique in Chinese Landscape Painting [PDF]

Huali Lan
openalex   +1 more source

Research on Building Space Model Method Based on Big Data Map Visual Design [PDF]

, 2022
Qiang Xu, Long He
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Space Research [PDF]

Nature, 1960
openaire   +2 more sources

Space based multicriteria analytics with hybrid weighting for flood risk management

Discover Analytics
Flooding, intensified by climate change and urbanisation, poses a major global threat, especially in developing countries. Traditional flood risk assessments are often costly and limited in scope.
Kenneth Uchua, John Essien, Adamson Oloyede, Funmilola Oluwafemi, Williams Adaji-Agbane, Uche Ekeson, Dapo Olatunbosun, Chiemeka Nsofor, Nazifa Bauka, Tijesuni Ogunrombi   +9 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Applying universality in the development of cascade processes for the research of high energy cosmic particles in space experiments [PDF]

, 2017
Anastasiya Fedosimova, P. B. Kharchevnikov, I.A. Lebedev, T. Temiraliev   +3 more
openalex   +1 more source