Results 71 to 80 of about 1,961,254 (314)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Exhibition “Space. Information. Research.”
Kartografija i Geoinformacije, 2015 The exhibition Space. Information. Research. was opened in ZgForum, premises of the City Office of Strategic Planning and Development of the City of Zagreb for communication with professional and the general public on December 18, 2014.
Darko Šiško
doaj
To the Edge of Space and Back: Cultivating Future Scientists through High-Altitude Research
, 2021 Brittany D. Chambers +3 more
openalex +2 more sources
Research on Constructing a Healing Environment for the Street Spaces of a High-Density City: Using Street Spaces in Macao’s Old City Area [PDF]
, 2020 Lingchao Meng, Chun Zhu, Kuo-Hsun Wen
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Lab-on-chip technologies for space research - current trends and prospects. [PDF]
Mikrochim Acta, 2023 Krakos A.
europepmc +1 more source
Research of a Flexible Space-Vector-Based Hybrid PWM Transition Algorithm between SHEPWM and SHMPWM for Three-Level NPC Inverters [PDF]
, 2020 Tao Jing +3 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source