Results 31 to 40 of about 10,502 (258)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A method for the automatic generation of inverse kinematic maps in modular robotic systems

open access: yesInternational Journal of Advanced Robotic Systems, 2016
Flexible manufacturing based on rapidly reconfigurable robotic systems will enable factories to meet time-sensitive and fast-changing industrial demands.
Mohammad Mayyas, Rochelle Mellish
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Providing a Bird Swarm Algorithm based on Classical Conditioning Learning Behavior and Comparing this Algorithm with sinDE, JOA, NPSO and D-PSO-C Based on Using in Nanoscience [PDF]

open access: yesJournal of Optoelectronical Nanostructures, 2020
There can be no doubt that nanotechnology will play a major role in our futuretechnology. Computer science offers more opportunities for quantum andnanotechnology systems.
Abdorreza Asrar   +2 more
doaj  

A Compact Bow-tie Shaped Wide-band Microstrip Patch Antenna for Future 5G Communication Networks [PDF]

open access: yesRadioengineering, 2021
In this paper, a novel compact bow-tie shaped microstrip patch antenna for wide-band application is presented. The proposed geometry consists of a modified bow-tie structure at the top of the Rogers RT-5880 substrate with a 50 Ω feed-line and 8 × 8 mm2 ...
D. G. Patanvariya, A. Chatterjee
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Infection Risk from Surgeons' Eyeglasses

open access: yesJournal of Orthopaedic Surgery, 2012
Purpose. To assess bacterial contamination of 20 eyeglasses from surgeons. Methods. 40 samples were taken from the nose pad (n=20) and earpiece (n=20) of 20 eyeglasses from orthopaedic surgeons using a sterile swab stick soaked in sterile distilled water.
Umer Butt   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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