Results 111 to 120 of about 136,014 (304)
Advanced Science, EarlyView.An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang +7 more
wiley +1 more source
, 2022 Smart city projects in Europe and North America are employing a novel approach to data analysis that processes hardly any or no personal data at all. As such, these projects—at least, for the most part—escape the scope of (European) data protection law ...
Galič, Maša
core
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Conjunction Analysis Software Suite for Space Surveillance and Tracking
AerospaceThe increasing number of objects in Earth orbit has encouraged the development of space surveillance and tracking (SST) applications. A critical aspect of SST is the identification and characterization of close encounters between pairs of space objects ...
Sergio Bonaccorsi +6 more
doaj +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Diverting and diverted glances at cameras: playful and tactical approaches to surveillance studies
, 2014 In the lines of Albrechtlund and Dubbled (2005) and their call for a new direction in Surveillance Studies, this paper discusses the overlapping of surveillance, art and entertainment.
Gangneux, Justine
core
Advanced Science, EarlyView.We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi +12 more
wiley +1 more source
A system design for space-based space surveillance
, 2014 This paper presents the capabilities of a Space-Based Space Surveillance (SBSS) demonstration mission for Space Surveillance and Tracking (SST) based on a micro- satellite platform. The results have been produced in the frame of ESA’s "As sessment Study
Utzmann, J. +6 more
core
Ferroelectric Devices for In‐Memory and In‐Sensor Computing
Advanced Science, EarlyView.Inspired by biological systems, in‐memory and in‐sensor computing overcome von Neumann bottlenecks. Ferroelectric devices can mimic synaptic functions and sense stimuli like light or force, therefore are ideal for these paradigms. This review introduces the ferroelectric devices applied for in‐memory and in‐sensor computing, covering their structures ...
Hong Fang +5 more
wiley +1 more source
Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source