Results 31 to 40 of about 4,522,701 (286)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A Refined Space Environment Index for the Characterization of In-Orbit Fragmentations
AerospaceWe introduce a refined formulation of the Fragmentation Environmental Index (FEI), designed to assess changes in the Low Earth Orbit (LEO) environment resulting from the fragmentation of a specific mass.
Luigi Gisolfi +2 more
doaj +1 more source
Remote Sensing, 2023 Space-based target surveillance is important for aerospace safety. However, with the increasing complexity of the space environment, the stellar target and strong noise interference pose difficulties for space target detection. Simultaneously, it is hard
Yueqi Su +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
DEVELOPMENT AND IMPROVEMENTS OF COMPUTATIONAL METHODS IMPLEMENTED TO THE COLITEC SOFTWARE
Odessa Astronomical Publications, 2018 The CoLiTec software is a large complex of processing modules that implements computational methods for the different purposes: brightness equalization of CCD-frames; automated calibration of the frames by bias-frame, dark-frame, and flat-field for ...
S. V. Khlamov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Surveillance to detect emerging space–time clusters [PDF]
Computational Statistics & Data Analysis, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Renato M. Assunção, Thaís Correa
openaire +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
‘Control Space?: Cinematic Representations of Surveillance Space between Discipline and Control’
, 2012 Recent developments in surveillance practices and their related technologies suggest that the heretofore dominant Foucauldian paradigm of discipline, with its sites of confinement in which space is “segmented, immobile [and] frozen”, may no longer be an ...
Muir, Lorna
core +1 more source