Results 71 to 80 of about 15,653,169 (406)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Unsupervised Spectrum Anomaly Detection Method for Unauthorized Bands

open access: yesSpace: Science & Technology, 2022
With the rapid development of wireless communication, spectrum plays increasingly important role in both military and civilian fields. Spectrum anomaly detection aims at detecting emerging anomaly signals and spectrum usage behavior in the environment ...
Yu Tian   +5 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

High‐Impulse, Modular, 3D‐Printed CubeSat Electrospray Thrusters Throttleable via Pressure and Voltage Control

open access: yesAdvanced Science
This study reports the proof‐of‐concept demonstration of novel, additively manufactured, droplet‐emitting electrospray emitter arrays for CubeSat thruster applications.
Hyeonseok Kim   +1 more
doaj   +1 more source

Decentralized Distributed Deep Learning with Low-Bandwidth Consumption for Smart Constellations

open access: yesSpace: Science & Technology, 2021
For the space-based remote sensing system, onboard intelligent processing based on deep learning has become an inevitable trend. To adapt to the dynamic changes of the observation scenes, there is an urgent need to perform distributed deep learning ...
Qingliang Meng   +4 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Cosmonauts challenge

open access: yesScience Museum Group Journal, 2015
Focusing on the experience of working with Russia’s cultural, industrial and political sectors, this paper investigates how the development of new contacts and partnerships has contributed not only to the loan of material of historic significance to the ...
Ian Blatchford, Dr Natalia Sidlina
doaj   +1 more source

Buber, educational technology, and the expansion of dialogic space

open access: yesAi & Society, 2018
Buber’s distinction between the ‘I-It’ mode and the ‘I-Thou’ mode is seminal for dialogic education. While Buber introduces the idea of dialogic space, an idea which has proved useful for the analysis of dialogic education with technology, his account ...
R. Wegerif, L. Major
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Technology Space Camp [PDF]

open access: yes2002 Annual Conference Proceedings, 2020
Comment: 12 ...
openaire   +2 more sources

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