Results 131 to 140 of about 2,159,529 (317)

Approaching stimuli bias attention in numerical space

, 2012
Increasing evidence suggests that common mechanisms underlie the direction of attention in physical space and numerical space, along the mental number line. The small leftward bias (pseudoneglect) found on paper-and-pencil line bisection is also observed
Longo, Matthew R., Francisco, A., Lourenco, S.F.   +2 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Space Syntax Based Agent Simulation

, 2001
Space syntax derives from a set of analytic measures of configuration that have been shown to correlate well with how people move through and use buildings and urban environments.
Turner, Alasdair, Penn, Alan, Turner, A., Penn, A.   +3 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The costs and benefits of providing open space in cities [PDF]

We use the monocentric model of a city to derive a simple cost-benefit rule for the optimal provision of open space. Although many researchers have investigated the value of open space in cities, few of them have compared it to the costs of providing ...
Jan Rouwendal, Willemijn Weijschede- v.d. Straaten   +1 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Report: RHOA and RCA Land Use Committee, "Final Report of the RHOA and RCA Land Use Committee," May 1984

, 2007
Textual: Report, copy; 11” x 8.5” (27.9 cm x 21.6 cm)Report from RHOA and RCA Land Use Committee entitled "Final Report of the RHOA and RCA Land Use Committee" dated May 1984. This report, submitted to the boards of the Reston Home Owners Association and
RHOA and RCA Land Use Committee
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Dorsal CA1 lesions of the hippocampus impact mating tactics in prairie voles by shifting non-monogamous males’ use of space to resemble monogamous males

Frontiers in Behavioral Neuroscience
Alternative mating tactics within mating systems are characterized by discrete patterns of spatio-temporal overlap with same-and opposite-sex conspecifics and mating-relevant outcomes.
Lindsay L. Sailer, Caitlyn J. Finton, Pooja P. Patel, Steven M. Bogdanowicz, Alexander G. Ophir   +4 more
doaj   +1 more source

Development and Application of an Activity Based Space-Time Accessibility Measure for Individual Activity Schedules [PDF]

Accessibility is an important aspect of human existence impacting on our notion of society equity and justice. It plays an important role in a number of existing theories of spatial and travel behaviour in addition to affecting the rate and the pattern ...
Olu Ashiru, John Polak, Robert B. Noland
core